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Doctor Mike Hansen - The most important bloodwork to check your health status

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Short Summary

Main recommendation: Check fasting insulin levels, not just hemoglobin A1c and fasting glucose, to detect insulin resistance early, and keep fasting insulin below 10 microunits per milliliter through diet and exercise. The speaker argues that insulin resistance drives high cholesterol, high blood pressure, type 2 diabetes, heart disease, stroke, fatty liver disease, gout, dementia, and 13 obesity-related cancers. He says that by the time A1c and glucose rise, insulin resistance is already well developed.

Key Points

  • Fasting insulin is the best marker of insulin resistance for people who do not have type 1 diabetes or insulin-dependent type 2 diabetes, because those groups do not make insulin or are already on insulin.
  • Insulin resistance develops when the pancreas produces too much insulin over a long period, causing insulin receptors on cells to down-regulate and bind insulin less effectively.
  • The speaker says type 2 diabetes can be treated and sometimes reversed through diet, exercise, and, in some cases, GLP-1 drugs such as Mounjaro or Ozempic, and disputes the American Diabetes Association's position that it has no treatment or cure.
  • Insulin resistance blocks weight loss because insulin keeps signaling fat cells to store energy, so insulin must come down first.
  • Protein type and amount affect insulin: the speaker says excess branched-chain amino acids (leucine, isoleucine, valine), especially from corn-fed beef or protein powders, can be converted by the liver into fat or glucose and raise insulin.

Details Worth Noting

  • Concrete instructions:
    • Ask your doctor to check fasting insulin, since many doctors do not routinely order it, possibly due to insurance coverage or familiarity.
    • Aim for fasting insulin below 10 microunits per milliliter, with lower being better; the speaker's own level was 3.3, and a healthy marathon runner may be 2 to 3. Above 15 indicates insulin resistance.
    • Lower insulin by avoiding refined carbohydrates and added sugar, with a suggested limit of under 25 grams of added sugar and refined carbohydrates per day.
    • Eat about 25 to 30 grams of fiber per day from real food such as seeds, nuts, fruits, vegetables, beans and legumes, and whole intact grains; most people eat only 11 to 15 grams.
    • Match protein intake to your goals: build muscle with protein as needed, but avoid excess BCAAs if you are not a bodybuilder, and note that beef (especially corn-fed) and many protein powders are high in BCAAs, since BCAAs are found in high concentrations in corn products.
  • The speaker says eating fat does not raise insulin.
  • Bariatric surgery is an option but is invasive and risky; GLP-1 drugs lower insulin well but require weekly injections and are expensive.
  • The speaker presents these as his views and not professional medical advice.

Bottom Line

Fasting insulin is the earliest practical signal of metabolic trouble, and keeping it low through reduced added sugar, more fiber, and mindful protein intake is the speaker's core strategy for protecting long-term health.

Facts

  1. According to Dr. Mike Hansen, fasting insulin changes well before hemoglobin A1c levels rise, making it an earlier marker of metabolic dysfunction.

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