Short Summary
Main recommendation: Intermittent fasting of roughly one day, performed routinely, may lower the risk of coronary artery disease and diabetes, according to Dr. Ben Horn of Intermountain Medical Center, though he describes the research as preliminary. Dr. Horn suggests that, for the average person, fasting once a month may be sufficient if sustained over decades, and that people should drink water while fasting.
Key Points
- Dr. Horn's team previously studied roughly one-day fasts in their cardiac patient population and found reduced risk of coronary artery disease and diabetes among those who fast routinely as part of their lifestyle.
- Proposed mechanisms include the body entering a self-protection mode under food-deprivation stress, a large increase in human growth hormone, and a shift to using fat for fuel, which may reduce insulin resistance by lowering body fat.
- Dr. Horn says fasting appears to have a strong effect, but the research is very preliminary, and the team is moving toward interventional trials asking higher-risk individuals to fast more frequently.
- Other centers studying fasting so far examine it mainly as a weight-loss approach, whereas Dr. Horn's team is looking at broader heart and diabetes benefits.
- The team is running clinical trials and hospital-based studies, and is presenting 16 studies at the American College of Cardiology conference in Washington, DC — the most of any institution in the US, according to Dr. Horn.
Details Worth Noting
- Concrete instructions:
- Drink water while fasting, because dehydration is a risk factor for stroke.
- For the average person, the transcript suggests fasting about once a month, sustained over a period of decades, may be sufficient.
- Fasting is discussed as a lifestyle practice rather than a weight-loss tool; no specific schedule beyond these points was given.
- Fasting duration in the study was approximately one day; the transcript does not specify other lengths (half-day or two-day fasts) as validated.
- Dr. Horn cautions that it is not completely clear yet what the healthiest approach is, and that outcome data are still being gathered.
- Fasting is compared to medication only in terms of effect; the speaker notes it may be among the strongest non-pill approaches, but this is described as tentative.
- This is research commentary from the interview, not individualized medical advice; consult a clinician before changing eating or medication habits.
Bottom Line
Dr. Horn's findings suggest routine fasting may be linked to lower heart and diabetes risk, but the evidence is early and the optimal frequency and fasting length remain unsettled.





